P-ISSN: 2707-8345, E-ISSN: 2707-8353
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International Journal of Case Reports in Orthopaedics
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2025, Vol. 7, Issue 1, Part B

Vanishing bone disease-like presentation in a middle-aged male due to primary hyperparathyroidism: A rare presentation


Author(s): Satyajeet Raj, Vikash Kumar Rai and Rohit Kr Sahani

Abstract: Vanishing bone disease (VBD), also known as Gorham-Stout disease, is typically idiopathic and characterized by progressive osteolysis. However, secondary causes mimicking VBD-like bone loss must be considered, especially in adults. We present a rare case of a 46-year-old male with progressive femoral osteolysis and renal calculi, ultimately diagnosed with primary hyperparathyroidism (PHPT) due to a parathyroid adenoma. Following parathyroidectomy surgery value of parathyroid hormone (PTH) reduced significantly and patient improved clinically. This case highlights the importance of metabolic and endocrine evaluation in osteolytic conditions and demonstrates a reversible form of “vanishing” bone loss.

DOI: 10.22271/27078345.2025.v7.i1b.252

Pages: 97-99 | Views: 58 | Downloads: 26

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International Journal of Case Reports in Orthopaedics
How to cite this article:
Satyajeet Raj, Vikash Kumar Rai, Rohit Kr Sahani. Vanishing bone disease-like presentation in a middle-aged male due to primary hyperparathyroidism: A rare presentation. Int J Case Rep Orthop 2025;7(1):97-99. DOI: 10.22271/27078345.2025.v7.i1b.252


International Journal of Case Reports in Orthopaedics
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