Abstract: Lipomas are the most common adipose soft tissue tumours. They are called “giant” when the excised piece exceeds 5 cm in diameter. This observation concerned a 55-year-old right-handed patient who consulted for the management of a right palmar mass that had been evolving for more than ten years. Excision of the mass was carried out. The postoperative course was uneventful, with wound healing by first intention. She was referred to physiotherapy for a complete functional recovery of the fingers. Histopathology conclusively showed it to be a conventional lipoma.